Question

Explain why the male serum reference range of creatine is higher than that of the female

Answer 1

Creatinine and creatinine clearance tests measure the level of the waste product

The amount of creatinine in the blood increases with muscle mass, men usually have higher creatinine levels than do women. Generally, a high serum creatinine level means that your kidneys aren't working well. It's especially important to manage blood   pressure, which often requires medication.

Women had different renal diagnoses, less proteinuria and lower serum creatinine levels for given GFRs than men. the younger women had lower mean arterial pressure than did the men. Older women compared with younger had higher mean arterial pressure, body weight and body mass index, and total low density lipoprotein cholesterol. These differences were not seen between males of the same two age groups. However,the inulin clearance gives a valid measure of the glomerular filtration rate.GF is the main index for working of kidney.

Creatinine concentrations is high due to higher muscle mass; a correlation between body mass index (BMI) and creatinine concentrations has been described only in male .