Question

In: Biology

Which cytosines are methylated in the eukaryotic genome and which are not? Where in the genome...

Which cytosines are methylated in the eukaryotic genome and which are not? Where in the genome are cytosines “protected” from methylation?

Solutions

Expert Solution

  • Methylation of cytosines takes place,where the cytosine that preceded a guanine nucleotide or CpG SITES.
  • NON CpG SITES are methylated in embryonic stage only
  • Mature NON CpG SITES are not methylated. (cytosines that are not preceded with guanine nucleotide)
  • CYTOSINES are protected from methylation in CpG ISLANDS Of genome.(especially those associated with promoters)

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