Question

1. Briefly describe three ways that insulin is stimulated? A direct response to high glucose is not an acceptable answer.

2. What is the clinical relevance of detecting glucose in the urine?

Answer 1

1. The abnormal increase of insulin in the blood circulation is called Hyperinsulinemia.There may be many reasons for this Hyperinsulinemia except high blood glocose like-

• Metabolic Syndrome: Metabolic orders like hypertension,obesity,dislipidemia,glucosee intolerance can cause the pathogenic condition of hyperinsulinemia.
• Auto-immuno disease: If the receptor of the beta cell is affected by the auto-immuno disease can cause pathogenic condition of hyperinsulinemia.
• Drugs: Some times drugs are also responsible for the abnormal productioon of insulin and results hyperinsulinemia.

2. The presence of glucose in the urine indicate some disease like-

• Hyperglycemia: If the blood glucose level is higher than the normal range then the glucose can be detected in the urine of the individual.
• Renal disfunction: If the nephrone of the kidney is unable to reabsorbe the filtrate glucose,so it may be detected in the released urine.