In: Biology
what are the genes and genetic controls governing the Entner Doudoroff pathway? Explain in great detail
Answer
Gene: It is a segment of DNA transcribe into coding mRNA and mRNA
translated into functional protein molecule such as enzyme.
Enzyme are the protein helps in driving the chemical reaction in
which reactant molecule is converts into product. Many of the
metabolic pathways are. Mediate by several enzymes.
Here we have discussed the Entner-Doudoroff pathway
1. In this pathway initially glucose after adding
phosphate converts into glucose -6-phosphate by hexokinase
enzyme.
2. Then removal of hydrogen ion from
Glucose-6-phosphate and convert into
6-phosphogluconolactone by the enzyme glucose-6-phosphate
dehydrogenase. Additionally molecule of NADPH release.
3. 6-phopshogluconolactone is converted into
6-phosphogluconate by hydrolase enzyme
4. Dehydration can change 6-phosphogluconate to 2-keto
3-deoxy 6-Phosphogluconate by 6-phosphogluconate
dehydrogenase.
5. Further, 2-keto 3-deoxy 6-Phosphogluconate. Split to
form pyruvate and glceraldehyde-3-phosphate by 2-keto 3-deoxy
6-Phosphogluconate aldolase enzyme
6. Generated Glyceraldehyde-3-phosphate act as
precursor in glycolysis cycle and undergo many step to convert into
pyruvate (end product of glycolysis).