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In: Biology

what are the genes and genetic controls governing the Entner Doudoroff pathway? Explain in great detail

what are the genes and genetic controls governing the Entner Doudoroff pathway? Explain in great detail

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Answer
Gene: It is a segment of DNA transcribe into coding mRNA and mRNA translated into functional protein molecule such as enzyme.
Enzyme are the protein helps in driving the chemical reaction in which reactant molecule is converts into product. Many of the metabolic pathways are. Mediate by several enzymes.
Here we have discussed the Entner-Doudoroff pathway

1.   In this pathway initially glucose after adding phosphate converts into glucose -6-phosphate by hexokinase enzyme.
2.   Then removal of hydrogen ion from Glucose-6-phosphate and convert into
6-phosphogluconolactone by the enzyme glucose-6-phosphate dehydrogenase. Additionally molecule of NADPH release.
3.   6-phopshogluconolactone is converted into 6-phosphogluconate by hydrolase enzyme
4.   Dehydration can change 6-phosphogluconate to 2-keto 3-deoxy 6-Phosphogluconate by 6-phosphogluconate dehydrogenase.
5.   Further, 2-keto 3-deoxy 6-Phosphogluconate. Split to form pyruvate and glceraldehyde-3-phosphate by 2-keto 3-deoxy 6-Phosphogluconate aldolase enzyme
6.   Generated Glyceraldehyde-3-phosphate act as precursor in glycolysis cycle and undergo many step to convert into pyruvate (end product of glycolysis).


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