In: Biology
Interferons (select the INCORRECT statement)
Interferons are components of the innate immune system that are produced in response to a viral infection. |
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The gene that encodes a given interferon molecule is present in the viral genome and is introduced into the host cell when a virus infects that cell. |
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Interferons act in a paracrine manner and bind to cell surface receptors on neighboring host cells. |
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Activation of interferon receptors on a host cell leads to the expression of antiviral proteins that prevent viral replication in that host cell. |
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A virus can invade a host cell that has activated interferon receptors on its surface. |
*The gene that encodes a given interferon molecule is present in the viral genome and is introduced into the host cell when a virus infects that cell
Most virus-infected mammalian cells produce a set of proteins called interferons, which are released and react with uninfected cells so as to render them resistant to infection with viruses. Interferons are a family of naturally-occurring proteins that are made and secreted by cells of the immune system of the host ,for example, white blood cells, natural killer cells, fibroblasts, and epithelial cells. All mammalian species have complex families of genes encoding different subtypes of interferon a, and one or two interferon β genes. Nonmammalian vertebrates have interferon β genes but no interferon α genes. Human immune interferon gene is located on chromosome 12. So interferone genome is not present in the viral genome but present in host genome.