If the phosphoglycerate mutase reaction the side chain of which as in thE enzyme is transiently...

If the phosphoglycerate mutase reaction the side chain of which as in thE enzyme is transiently phosphorylated as part of the reaction .,

Solutions

Expert Solution

Answer. His residue of the enzyme

Glycolysis is an ancient catabolic pathway which leads to breakdown of 1 molecule of glucose to 2 molecules of pyruvate yielding net 2ATP molecules.

Glycolysis

The enzyme phosphoglycerate mutase catalyzees the conversion of 3-phosphoglycerate to 2-phosphoglycerate. This occurs via an exchange of phosphate involving a His residue of the enzyme.

His residue on the enzyme has a phosphate group attached to it.
This is tranferred to the substrate (3-phosphoglycerate) to form 2,3-bisphosphoglycerate.
The phosphate group at the C-3 is tranferred to the His residue of the enzyme, thus generating the product (2-phosphoglycerate).

gladiator answered 1 year ago

Next > < Previous

Related Solutions

The enzyme enolase catalyzes the following reaction in the glycolysis pathway (Chapter 14): 2-phosphoglycerate ® phosphoenolpyruvate...

The enzyme enolase catalyzes the following reaction in the glycolysis pathway (Chapter 14): 2-phosphoglycerate ® phosphoenolpyruvate + H2O Dehydration of 2-phosphoglycerate (2PG) results in phosphoenolpyruvate (PEP), which is a high-energy phosphate donor that can be used to phosphorylate ADP to make ATP. Thus, this is an important reaction to set up the final step of the pathway. Balantidiasis is a disease caused by the ciliated protozoan, Balantidium coli. As it is a eukaryote, antibiotics against bacteria will not affect it....

Phosphoglycerate kinase is an important enzyme in the glycolysis. The conversion of 1,3-Bisphosphoglycerate reacts under standard...

Phosphoglycerate kinase is an important enzyme in the glycolysis. The conversion of 1,3-Bisphosphoglycerate reacts under standard conditions with release of 18,8 kJ pr mol. Hydrolysis of adenosine triphosphate is spontaneous under liberation of 30,4 kJ/mol. a) Write the complete reaction and calculate ΔG’ for the reaction occurring at 37 °C and pH 7, when it is known that the concentration of adenosine triphosphate, adenosine diphosphate, glycerate-3-phosphate and 1,3-bisphosphoglycerate is 1.25mM, 0.1mM, 1.0 mM and 1μM, respectively. b) Calculate the ratio...

Which of the following is the final result of the five-step chain reaction on which the...

Which of the following is the final result of the five-step chain reaction on which the philosophy of total quality management (TQM) is based? a. Improvement in productivity b. Better use of time and materials c. Increase in a company's profitability d. Creation of more jobs e. Higher market share due to superior quality of products

“Rate enhancement” of a chemical reaction by an enzyme compares which of the following values? a....

“Rate enhancement” of a chemical reaction by an enzyme compares which of the following values? a. kforward vs. kreverse b. k without enzyme and kcat with enzyme c. kcat/KM without enzyme and kcat/KM with enzyme d. Vmax without enzyme and Km with enzyme e. kcat with enzyme and kdiffusion

Which of the following amino acids has a side chain that can serve as a hydrogen...

Which of the following amino acids has a side chain that can serve as a hydrogen bond donor (but not acceptor) in its predominant form at pH 7? D K M V N

Which enzyme unwinds? Which enzyme prevents supercoiling? Which enzyme lays down RNA? Which enzyme replaces the...

Which enzyme unwinds? Which enzyme prevents supercoiling? Which enzyme lays down RNA? Which enzyme replaces the primer? Which enzyme connects Okazaki fragments?

An explosion is possible in a chain reaction when A. the reaction includes a chain branching...

An explosion is possible in a chain reaction when A. the reaction includes a chain branching step B. a termination step is the fastest step C. the reaction has a positive free energy change D. the reaction is endothermic

Which of the following is NOT a required component of a polymerase chain reaction (PCR)? A)...

Which of the following is NOT a required component of a polymerase chain reaction (PCR)? A) deoxynucleotides B) two primers C)DNA ligase D)heat stable DNA polymerase E) none of the above (i.e. all the above are required components of a PCR) E)

The side chain of Asp 94 on the b chain of hemoglobin is in close proximity...

The side chain of Asp 94 on the b chain of hemoglobin is in close proximity to the imidazole ring of His 146 on the b chain in the deoxy form of hemoglobin but not the oxy form. 1. What kind of interaction occurs between Asp 94 and His 146 in the deoxy form of hemoglobin? 2. Is the imidazole ring of His protonated or unprotonated? Explain. 3. The proximity of Asp 94 alters the pK value of the imidazole...

25) Am enzyme-catalyzed reaction proceeds at a faster rate than an uncatalyzed reaction because the enzyme...

25) Am enzyme-catalyzed reaction proceeds at a faster rate than an uncatalyzed reaction because the enzyme lowers the difference in free energy between the reactants and the products. a. True b. False

Subjects