In: Biology
Place the following scenario in order of how it would occur... 1 to 7
S.typhimurium cells are allowed to grow and proliferate through various virulence factors which further allows it to express more virulence factors.
S.typhimurium cells use oral fecal route from infected host to leave one host and enter another host via potential contaminated surfaces or common sources.
S.typhimurium cells spreads along the lower GI tract (smaller intestine and larger intestine), virulence factors like enterotoxins create ion imbalance
You and your friends are out for a late night meal and you eat some undercooked chicken. Your system is exposed to S.typhimurium
S.typhimurium extracellular factors like Type 1 Fimbriae bind onto epithelial cells of the intestines.
Ion imbalance cause influx of water into the lumen while endotoxins cause symptoms like fever.
Various antigens present on S.typhimurium evade host systems like phagocytosis or macrophage detection.
Answer :
Salmonella Typhimurium is a pathogenic gram negative bacteria found in intestinal lumen. Its usually spread by feco oral route. Mainly by undercooking. Causes diseases typhoid. Typhoid toxins are life threatening.