Question

1.) How many milligrams of sodium chloride should be used in compounding the prescription?

Rx
Ephedrine Sulfate (0.2)	0.30 grams
Sodium chloride	q.s.
Purified water ad	30 milliliters
Make isotonic solution
Sig use as directed

*Type in your answer to 2 decimal places. Do not forget the unit

2.)

Rx
Oxytetracycline HCl (0.12)	2%
Chlorobutanol sol. (0.24)	0.01%
Sodium chloride	q.s.
Sterile water ad	30 mL
Make a solution isotonic with tears.

How many milliliters of a 0.9% solution of NaCl should be used to prepare the prescription?

*Type in your answer to 2 decimal places. Do not forget the unit

Answer 1

Rx
Ephedrine Sulfate 0.3 g

Sodium Chloride q.s.

Purified Water ad 30 mL

Make isoton. sol.

• Step 1.
0.23 x 0.3 g = 0.069 g of sodium chloride represented by the Ephedrine sulfate.
Calculate the amount (in grams) of sodium chloride by the ingredients in the prescription then multiply the amount of each substance by its sodium chloride equivalent.

• Step 2. Calculate the amount of sodium chloride, alone, that would be contained in an isotonic solution of the volume specified in the prescription, and the amount of sodium chloride in a 0.9% solution of the specified volume.

30 x 0.009 = 0.270 g of sodium chloride in 30 mL of an isotonic sodium chloride solution

• Step 3.Subtract the amount of sodium chloride represented by the ingredients in the prescription

(Step 1) from the amount of sodium chloride, alone, that would be represented in the specific volume of an isotonic solution

(Step 2). The answer represents the amount (in grams) of sodium chloride to be added to make the solution isotonic.

Step 3.
0.270 g (from Step 2) - 0.069 g (from Step 1) = 0.201 g of sodium chloride to be used.