Which of the following causes change in nucleosome structure by utilizing ATP hydrolysis, loosens or tightens...

Which of the following causes change in nucleosome structure by utilizing ATP hydrolysis, loosens or tightens DNA, and alters DNA accessibility to proteins?

A. Histones

B. Kinases

C.Cohesins

D. Chromatin remodeling complexes

Expert Solution

The correct answer is option D.

D. Chromatin remodeling complexes

The chromatin remodelling complexes are classified into two major groups:

(1) ATP-dependent complexes, these complexes use the energy by ATP hydrolysis to disrupt the association of histones with DNA.

(2) Histone acetyltransferase and deacetylase complexes, these regulate the acetylation in transcription at the amino terminal domains of the nucleosomal histones.

These complexes are involved in the DNA accessibility to transcriptional proteins and modifies the DNA by loosens or tightens it.

gladiator answered 2 years ago

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