Question

In: Anatomy and Physiology

Which of the following proteins as a shaft and double head which binds with ATP and...

Which of the following proteins as a shaft and double head which binds with ATP and the thin filament
Myosin
Troponin
tropomyosin

Solutions

Expert Solution

Correct Answe is Option A -Myosin

EXPLANATION

Troponin is a protein complex present in the thin filament of muscle contraction.Troponin has 3 main subunit they are Troponin T, Troponin I and troponin C .

Troponin T help to biind the troponin to the tropomyosin

Troponin I help to bind with the Actin filament

Troponin C binds with the calcium which help to displace the Tropomyosin complex from the cative site of the actin.

Tropomyosin is a linear polymer which is seen over the actin filament.

function of tropomyosin is to protect the actin from binding with the myosin until a nerve signal arrives.

Hence option B and C is wrong

Myosin contain a Head, neck , and a tail

Head is double headed which contain Actin binding site and ATP binding site seperately

Neck is the short region in between the Head and tail .

Head and neck together called cross arm

When the calcium released from the sarcoplasmic reticulum bind with the troponin C , the tropomyosin is shited from the active site of the actin .

Myosin head will come and fuse in the active site of the actin and the actin slide over the myosin to produce muscle contraction.

Hence Option A is correct


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