How will you describe and contrast on enzyme activity based on Km and Vmax from Michaelis...

How will you describe and contrast on enzyme activity based on Km and Vmax from Michaelis menten equation? (low or high Km/Vmax)
what does it mean when Km is High or low
what does it mean when Vmax is High or Low

Expert Solution

In Michaelis menten equation, Km is defined as the concentration of substrate at which the activity of enzyme is half of its maximum value.

The Vmax is defined as the maximum velocity of an enzyme at which the enzyme catalyses the reaction.

Both Vmax and Km values are inversely proportional to each other.

A high value of Km would mean that higher concentration of substrate would be required to achieve Vmax/2, that is Vmax will be lower.

A low value of Km would mean that lower concentration of substrate would be required to achieve Vmax/2, that is Vmax will be higher.

A high value of Vmax would mean that the Km value will be lower and low value of Vmax would mean that Km value would be higher.

gladiator answered 2 years ago

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