Explain the genetics of schizophrenia?

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Schizophrenia is a common psychiatric disorder strong genetic component. The genetic liability of schizophrenia is now established as polygenic with alleles in many genes existing across the full allelic frequency spectrum. It has also become apparent that schizophrenia shares risk alleles with other neuropsychiatric phenotypes such as bipolar disorder, major depressive disorder, autism spectrum disorder,intellectual disability, and attention deficit hyperactivity disorder . This risk variants aggregate in several sets of functionally related genes thereby providing novel insight into disease, pathogenesis and opportunities.

The cause of schizophrenia is:-

* Biological influence that is genetics,

10 percentage chance in family and 46 percentage chance for both parents have the disorder

* Neurochemical factors:-changes the activity of one or more neurotransmitters

* Structural abnormality of the brain: often show sign of deteriorated brain tissue and, sometimes enlargement of brain ventricles.

Nightingale answered 2 years ago

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