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trace the route of biosynthesis and the storage of hlucose, fatty acids and amino acids

trace the route of biosynthesis and the storage of hlucose, fatty acids and amino acids

Solutions

Expert Solution

The route of biosynthesis of glucose:

The synthesis of glucose from noncarbohydrate precursors, a process called gluconeogenesis.

The gluconeogenic pathway converts pyruvate into glucose. Noncarbohydrate precursors of glucose are first converted into pyruvate or enter the pathway at later intermediates such as oxaloacetate and dihydroxyacetone phosphate.

Storage of glucose:

Glucose that is not needed for energy is stored in the form of glycogen as a source of potential energy, readily available when needed. Most glycogen is stored in the liver and in muscle cells. When these and other body cells are saturated with glycogen, excess glucose is converted to fat and is stored as adipose tissue.

The route of biosynthesis of fatty acids:

The creation of fatty acids from acetyl-CoA and NADPH through the action of enzymes called fatty acid synthases. This process takes place in the cytoplasm of the cell. Most of the acetyl-CoA which is converted into fatty acids is derived from carbohydrates via the glycolytic pathway.

Storage of fatty acids:

Fatty acids stored as tryglicerides in adipose tissues.

The route of biosynthesis of amino acids:

All amino acids are derived from intermediates in glycolysis, the citric acid cycle, or the pentose phosphate pathway.  Nitrogen enters these pathways by way of glutamate and glutamine.

Amino acids that are synthesized in mammals are called the nonessential amino acids to denote the fact that they are not needed in the diet. The essential amino acids, must be obtained from food.

Storage of amino acids:

The amino acids are transported into the bloodstream for dispersal to the liver and cells throughout the body to be used to create new proteins. When in excess, the amino acids are processed and stored as glucose or ketones.


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