1)The therapeutic action of13-adrenergic receptor blockers such as propranolol in angina pectoris is believed to be...

1)The therapeutic action of13-adrenergic receptor blockers such as propranolol in angina pectoris is believed to be primarily the result of
a. Reduced production of catecholamine’s
b. Dilation of the coronary vasculature
c. Decreased requirement for myocardial oxygen
d. Increased peripheral resistance
e. Increased sensitivity to catecholamine’s

2Which of the following drugs is considered to be most effective in relieving and preventing ischemic episodes in patients with variant angina?
a. Propranolol
b. Nitroglycerin
c. Sodium nitroprusside
d. Nifedipine
e. Isosorbide dinitrate

3) A 69-year-old male with angina develops severe constipation following treatment with
a. Propranolol
b. Captopril
c. Verapamil
d. Dobutamine
e. Nitroglycerin

Expert Solution

Ans1 c is a correct answer.

Propranolol is decreases the mycardial oxygen requirements to release or prevent anginal pain and death of myocardial tissues. It also blocks the catecholamines increase hearth rate, blood. Pressure and myocardial contraction.

Ans2. Option d is a correct answer.

Variant angina causes vasospasm, mycardium require calcium ion for contraction nifedipine provide slow movement of calcium into the myocardialand smooth muscle cells.

Rest option are incorrect as propanol inhibition the CA ions movement, sodium nitroprusside is used for hypertension by dialation of periferal system.

Ans3 option e is a correct answer

As verapamil is a inhibiting the calcium movement in the coronary and vascular smooth muscle cells which result in inhibition of smooth muscle cells contraction. The intestine are lined by the smooth muscle, due the calcium inhibition effect, excessive vasodilation occur which result to constipation. And hypotension, letheragy are also some effect of this drugs.

It is should be encouraged the patient to take dietary fiber in diet to prevent constipation.

FOR ANY DOUBT POST A QUESTIONS IT WILL BE HIGHLY APPRECIATED ?

Nightingale answered 2 years ago

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