Question

In: Biology

What process results in the removal of the glucosyl residue from the nonreducing end of the...

What process results in the removal of the glucosyl residue from the nonreducing end of the glycogen molecule by the addition of orthophosphate?

Group of answer choices

- phosphorolysis

- glycolysis

- dephosphorylation

- hydrolysis

- phosphorylation

Solutions

Expert Solution

The correct option is phosphorolysis.

Glycogen breakdown is catalyzed by the enzyme glycogen phosphorylase. It catalyzes the cleavage of 14 linkage between two glucose molecules at the non-reducing end of glycogen. An inorganic phosphate attacks this linkage resulting in the removal of the glucose molecule as -D-glucose-1-phosphate. This is a phosphorolysis reaction.

Glycolysis cannot be the correct option because it is a complete process all together.

Dephosphorylation cannot be correct because it is the removal of a phosphate group from a molecule.

Hydrolysis is caused by the breaking of a water molecule. No energy is conserved in hydrolysis whereas in phosphorolysis, some energy is conserved by the formation of glucose-1-phosphate. So, hydrolysis cannot be correct.

Phosphorylation cannot be correct because it is the addition of a phosphate group to a molecule.


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