In: Biology
Fill in the blank.
Duchenne muscular dystrophy is caused by an X-linked recessive mutation in the DMD gene, which encodes the protein dystrophin. A female without the disease mates with a male with Duchenne muscular dystrophy; they have two sons and two daughters. The first son has the disease as does their first daughter.
Based on this, the probability that the second son will have the disease is________________
The probability that the second daughter will be a carrier is____________
Answer:
25 % for second son will have disease and 25 % for second daughter will be a carrier.
From the data given, the genotype of father and mother is predicted by applying pedigree and then punnet square calculation was done to find the probability.