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DMD is a x linked recessive inherited muscle weakness disorder , occuring mainly boys in early ages . it is caused by a mutation in gene that cause decreased production of one important muscle protien known as dystrophin. this protien is important for maintain the muscle fibres cell membrane, muscle weakness usualy begins in thigh muscles and follow in upward direction ,the child help himself to get up with upper extremties , first by rising to stands on his arms and knees and then walking his hands up his legs to stand upright, known as GOWER'S SIGN. the affected muscle looks bigger due to fat accumulation , known as psedudo hypertrophy of muscles . patient developes toe walking , frequent falls , lordosis , muscle contracture of achiles tendon , progressive difficulty in walking , may cause breathing difficulties ,... genetic testing can help in diagnosis.
blood examination shows high levels of creatine kinase .
treatments includes physical therapy , respiratory assistances , antiinflamatory medication like steroids , surgical .. even though no complete cure .