Trimethoprim and sulfamethoxazole (Septra) 8 mg/kg/day every 6 hours over 60 minutes x 8 doses. Weight...

Trimethoprim and sulfamethoxazole (Septra) 8 mg/kg/day every 6 hours over 60 minutes x 8 doses. Weight = 122 lb.

Weight in kilograms:

Dose Strength:

Total Strength:

Apparently the answers are: 55.45kg, 110.9mg, 443.6mg. I just want to know why this is the answer. The book does not specify why.

Solutions

Expert Solution

let us first note hte information provided in the question:

Recommended dose of septra - 8 mg/kg/day every 6 hourly

Weight of the patient - 122 lb

First step:

let us convert the weight from pounds to kgs

coversion factor: 1 kgs = 2.2 poounds (lb)

therefore:

1 kg = 2.2 Ib
'x' kgs = 122 lb
by cross multiplication
x kgs = 122 lb x 1 kg / 2.2 lb
x kgs = 122 x 1 kg / 2.2
x kgs = 55.45 kgs

Therefore the weight of the patient is 122 lb = 55.45 kgs

Second step:

Let us calculate the total dose of septra:

Recommended dose of septra - 8 mg/kg/day every 6 hourly

Weight of the dose - 55.45 kgs

8 x 55.45 kgs
443.6 mg per day

Therefore, the total dose for a day = 443.6 mg / day every 6 hourly

Third step:

Septra should be given every 6 hourly in 24 hours
Therefore,
- 24 hours / 6 hours = 4 times a day.
So, the total dose of Septra 443.6 mg should be given 4 times a day
443.6 mg / 4 = 110.9 mg (dose strength) should be the given 4 times a day.

Final answer:

Weight of the patient = 55.45 kgs
Dose strength = 110.9 mg of septra 4 times a day
Total dose strength = 443.6 mg of septra over 24 hours.

Nightingale answered 1 year ago

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