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Active learning template. Concept analysis on acute adrenal crises

Active learning template. Concept analysis on acute adrenal crises

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Expert Solution

Acute Adrenal Crisis

* Medical emergency caused by lack of cortisol.

Key points :-

* Cortisol - A steroid hormone (glucocorticoid) which deal with glucose metabolism.

*Adrenal cortex- Produces cortisol.

*pituitary gland - (anterior) regulates cortisol production by ACTH ( adrenocorticotropic hormone )

Causes :-

* Damage to the adrenal cortex

* Under treated addison's disease

* Adrenalectomy - removal of adrenal gland

* Damage to pituitary gland & no enough ACTH

Signs & symptoms :-

* Dehydration

* low blood pressure

* Sudden pain in stomach, back and legs

*Syncope

* Shock

* Severe Vomiting, diarrhoea, and headache

* Hyponatremia

* Hyperkalemia

* Hypoglycemia

Diagnosis :-

* electrolytes and glucose

*Baseline cortisol and ACTH

- send before steroid administration

* Renin random cortisol

*ACTH stimulation test

MAnagement :-

* Emergency management

- IV access

-Draw blood for stat electrolytes and glucose

- infuse 2-3 L of 0.9% saline or 5% dextrose in 0.9% saline solution.

- Administer cortisol stat

(Hydrocortisone along with iv fluids 100 mg every 6 hours )

-supportive management

* chronic management

- start glucocorticoids and mineralocorticoids

(Prednisone, hydrocortisone )

* Patient education

-Recognition & treatment of minor and major stress /illness

- clean evironment to prevent infection


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