Briefly state what happens to a mixture of compounds with different chemical properties, when this mixture...

Briefly state what happens to a mixture of compounds with different chemical properties, when this mixture is subjected to thin-layer chromatography.

Solutions

Expert Solution

Thin Layer chromatography (TLC) is a technique which is generally used for separating organic mixtures.
TLC consists of two phases, stationary phase and mobile phase. The mobile phase which is generally a mixture of a polar and non polar solvent. The stationary phase is the layer of silica particles. The interaction between molecules and silica particles plays the crucial rule to separate the compounds in the mixture.

As silica particles are polar, polar molecules get attached more to the silica particles. Then the solvent takes more time to elute. So, based on the polarity of the molecules, affinity with silica changes and thus the rise time increases.

So, more polar molecules will take more time to elute whereas less polar molecules will be separated first.

queen_honey_blossom answered 1 year ago

Next > < Previous

Related Solutions

State whether the following properties of a substance are physical properties or chemical properties: A. Substance...

State whether the following properties of a substance are physical properties or chemical properties: A. Substance boils at 1105 degrees Celsius. B. Density of the substance at 20 degrees Celsius is 1.738g/cm³. C. The substance burns in air. producing an intense white light. D. The substance reacts with chlorine to give a brittle white solid. E. The substance can be pounded into thin sheets or drawn into wires. F. The substance is a good conductor of electricity.

What types of compounds can be separated by HPLC but not GC? (Briefly describe properties.) short...

What types of compounds can be separated by HPLC but not GC? (Briefly describe properties.) short explaination please

Chemical properties of all organic compounds depends what types of functional groups are present. Explain this...

Chemical properties of all organic compounds depends what types of functional groups are present. Explain this concept using specific examples

briefly explain why is it important to know the chemical compounds that will bind to a...

briefly explain why is it important to know the chemical compounds that will bind to a particular dye molecule as well as the shape and size of the entire stained structure

briefly explain why is it important to know the chemical compounds that will bind to a...

briefly explain why is it important to know the chemical compounds that will bind to a particular dye molecule as well as the shape and size of the entire stained structure

1. What is Organic Chemistry? 2. Name two properties, physical or chemical that distinquish organic compounds...

1. What is Organic Chemistry? 2. Name two properties, physical or chemical that distinquish organic compounds from inorganic compounds? 3. What is the principal chemical bonding in organic compounds?

1. When an enzyme runs a chemical reaction, what happens to the enzyme at the end...

1. When an enzyme runs a chemical reaction, what happens to the enzyme at the end of the reaction? a) it is unchanged, and can run another reaction b) it is weakened, and is slower the next time c) it becomes part of the product, and is used up d) it is permanently damaged, or destroyed 2. When an enzyme accelerates a reaction rate, what does the enzyme do, thermodynamically (energy-wise)? a)lowers the activation energy for the reaction b) allows...

A) What happens when a software Interrupt occurs? Write steps briefly? &nbsp

A) What happens when a software Interrupt occurs? Write steps briefly? B) Differentiate between maskable and non-maskable interrupts? C) How are the multiplexed bus of 8086 demultiplexed? D) Find the address range when a 2K x 8 memory is interfaced with 8086/8088?

What happens to the properties of water, in particular, density, at sea level when ice melts...

What happens to the properties of water, in particular, density, at sea level when ice melts and the temperature increases to 4 degrees celsius? Give an example of this in practical terms. No practical answer can be repeated, you must use an original example. Do not use ice as the example.

What happens to the properties of water, in particular, density, at sea level when ice melts...

What happens to the properties of water, in particular, density, at sea level when ice melts and the temperature increases to 4 degrees C? Give an example of this in practical terms.

Subjects