Question

Ciprofloxacin Injection:

a. comments and additional medication info

b. The therapeutic effect of the medication

c. The action of the medication

d. Side effect or Adverse reactions of the medication

e. The recommended dose ranges

f. Contraindication of the medication

g. Life-threatening considerations

h. nursing intervention

PLEASE DO NOT COPY AND PASTE

Answer 1

Ciprofloxacin Injection

a. Comments and additional medication info :

• Ciprofloxacin injection is an antimicrobial agent given as an intravenous (IV) administration. It is used to treat bacterial infections.
• The medication should not be used for any disorder other than that for which it is prescribed.
• Do not give this injection to other people, even if they are showing the same symptoms.
• Patients should report any signs of adverse reactions to the physician.
• Ciprofloxacin should not be given to patients with myasthenia gravis, as it may worsen the condition.

b. The therapeutic effect of the medication:

• Urinary Tract Infections
• Lower Respiratory Tract Infections
• Chronic Bronchitis
• Skin Infections
• Bone and Joint Infections
• Acute Sinusitis
• Complicated Abdominal Infection
• Bacterial Prostatitis.

c. The action of the medication:

Ciprofloxacin is bactericidal antibiotic belonging to the class of Fluroquinolones. The inhibition of the enzymes topoisomerase II and topoisomerase IV, further inhibits the bacterial DNA replication, transcription, repair, and recombination. The inhibition, thereby enables Ciprofloxacin to act as a bactericidal.

d. Side effect or Adverse reactions of the medication: Ciprofloxacin can cause serious side effects, which include

• Tendinitis (Swelling or rupture of the tendons)
• Worsening of Myasthenia Gravis (muscle weakness)
• Peripheral Neuropathy (Nerve damage and or changes in sensation)
• Central Nervous System disorders such as Seizures, tremors, depression, anxiety, hallucinations, paranoia and confusion.
• Phototoxicity or Photosensitivity

e. The recommended dose ranges:

Pediatric dose - 6mg/kg to 10mg/kg every 8 to 12 hrs.

Adult dose – 200 - 400mg every 18 – 24 hrs.

f. Contraindication of the medication :

• Hypersensitivity – Contraindicated in patients with hypersensitivity to ciprofloxacin or any other drug of quinolone class of antibiotic.
• Tizanidine – Administration with Tizanidine is contraindicated.

g. Life-threatening considerations:

• Hepatotoxicity – cases of hepatotoxicity including hepatic necrosis and life threatening hepatic failure has been reported with the use of Ciprofloxacin IV.
• Hypersensitivity Reactions- Serious and fatal hypersensitivity reactions have been reported with the first dose of Ciprofloxacin.
• Concurrent administration of Ciprofloxacin IV accompanied by Theophylline have been reported to show serious and fatal reactions.

h. Nursing intervention

• To perform culture and sensitivity test before starting the therapy.
• Continuation of the medication for 2 days after the infection is cleared.
• Monitoring clinical response. If there is no improvement or there is a relapse occurring, repeat culture and sensitivity test.
• Encouraging the patient to complete the full course of the antibiotic therapy.