An alpha-thalassemia silent carrier man (αα/α-) mates with an alpha-thalasemia trait woman (αα /--). Assuming no...

An alpha-thalassemia silent carrier man (αα/α-) mates with an alpha-thalasemia trait woman (αα /--). Assuming no genetic recombination, which of the following genotypes is NOT possible in their offspring ?

αα /α-
1. α-/--
2. αα / αα
3. αα /--

4. α-/α-

Expert Solution

is the genotype which is not possible in their offspring.

In alpha thalasemia, an individual inherits two alpha globin genes from each parent.

Since, there is no recombination, an individual can inherit an intact chromosome from each parent without any recombination.

/ - is possible because will be inherited from woman and - will be inherited from man

- / -- is possible because - can be inherited from man and -- can be inherited from woman

/ is possible because each can be inherited from either man or woman

/ -- is possible because can be inherited from man and -- from woman

Only - / - is not possible because the man has a set of - but the woman doesn't have the other set.

______________________________

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gladiator answered 2 years ago

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