A woman who is a carrier for the cystic fibrosis (cf) allele
marries a man who...
A woman who is a carrier for the cystic fibrosis (cf) allele
marries a man who is also a carrier.
What percentage of the woman’s eggs will carry the cf
allele?____________
What percentage of the man’s sperm will carry the cf
allele?____________
The probability that they will have a child who carries 2
copies of the cf allele is equal to the percentage of eggs that
carry the allele times the percentage of sperm that carry the
allele. What is this probability?___________
Is this the same result you would generate when doing a Punnett
square of this cross?_____________
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CF carrier frequency estimations in American Hispanic
populations • Carrier screening kits for Cystic Fibrosis alleles
have been updated to include more probes (CFTR 60 kit 2) • It is
reported to have a detection rate of 83.7% in Hispanic American
populations.
The same group have a CF incidence of 1 in 9,500. Given the
above, determine:
1) CF carrier frequency in the Hispanic American population.
2) Estimate the probability of being a carrier if a CFTR 60 kit
result...
Hemophilia is a sex linked recessive condition. A woman who is a
carrier for hemophilia marries a man who is not a carrier.
a) What is the chance of their daughters having hemophilia?
b) What is the chance of their daughters being carriers for the
hemophilia allele?
A woman who is a carrier of hemophelia mates with a man with
hemophelia. Complete a punnett square.
How many of the children will have hemophelia? ___________
What percentage of the male children will not
have hemophelia? __________
If another man who can roll his tongue marries a woman who
cannot and they have ten children all of whom can roll their
tongues, what is his probable genotype? What is the genotype of the
children? The phenotype? Can you be sure of the man's genotype--why
or why not?
Cystic fibrosis is a rare disease caused by homozygosity for a
recessive allele, and characterized by a build-up of mucus in the
lungs and difficulty breathing. A woman whose maternal uncle had
the disease is trying to determine the probability she and her
husband could have an affected child. Her husband's sister died of
the disease. Assuming the uncle and the sister are the only family
members who had the disease, what is the chance that the couple's
first child...
Cystic fibrosis (CF) is a genetic disorder that affects mostly
the lungs, but also the pancreas, liver, kidneys, and intestine. CF
is inherited in an autosomal recessive manner with simple Mendelian
inheritance. It is caused by the presence of mutations in the gene
for the cystic fibrosis transmembrane conductance regulator (CFTR)
protein.
A normal couple intends to have children but consult a genetic
counselor because the man has a sister with CF and the woman has a
brother with CF....
Cystic fibrosis (CF) is an inherited disorder that
causes severe damage to the lungs, the digestive system and other
organs within the body. CF affects cells that produce thin and
slippery mucus and cause the secretions to become sticky and thick.
CF is caused by a deletion mutation on chromosome 7. In order for a
child to have cystic fibrosis they must inherit a defective gene
from each of his/her parents.
Rob and Jane have four children in this order:...
Cystic Fibrosis (CF) is a progressive genetic disease that
affects the lungs and digestive system as well as many other organ
systems. It causes thick, sticky mucus to build up in the lungs,
which leads to life-threatening lung infections. Cystic fibrosis is
caused by mutations in the gene that produces the cystic fibrosis
transmembrane conductance regulator (CFTR) protein. This protein is
responsible for regulating the flow of salt and fluids in and out
of the cells in different parts of...
Cystic fibrosis (CF) is a genetic disorder that affects mostly
the lungs, but also the pancreas, liver, kidneys, and intestine. CF
is inherited in an autosomal recessive manner with simple Mendelian
inheritance. It is caused by the presence of mutations in the gene
for the cystic fibrosis transmembrane conductance regulator (CFTR)
protein. A normal couple intends to have children but consult a
genetic counselor because the man has a sister with CF and the
woman has a brother with CF....