After the synthesis of RNA from DNA via transcription, RNA is processed in a number of...

After the synthesis of RNA from DNA via transcription, RNA is processed in a number of ways before it is released from the nucleus. What are the steps to RNA processing?

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Expert Solution

Generally in prokaryotes RNA Processing is not too much because of no nucleus. And in Eukaryotes RNA processing involves many steps.

A freshly synthesized RNA transcript is pre-mRNA after Processing it is called mRNA(messanger RNA).

The various steps involved in RNA processing are as follow:-

Splicing - It is the removal of introns(non-coding regions) and joining of exons(coding regions).

Capping - capping is adding of 7-methylguanosine triphosphate to the 5′ end of the growing transcript by a 5′-to-5′ phosphate linkage. This process prevent nascent RNA from degradation.

Tailing - tailing is adding of poly A tail at the 3' end. An enzyme called poly (A) polymerase (PAP) is part of the same protein complex that cleaves the pre-mRNA and it immediately adds a string of approximately 200 A nucleotides, called the poly (A) tail, to the 3′ end of the just-cleaved pre-mRNA. The poly (A) tail protects mRNA from degradation and helps in the export of the mature mRNA to the cytoplasm

gladiator answered 1 year ago

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