The physician orders Keflex 250 mg oral every 6 hours for a child weighing 40 lb....

The physician orders Keflex 250 mg oral every 6 hours for a child weighing 40 lb. The Keflex is available in a 250 mg/ 5 mL concentration. The recommeneded dose is 50 to 100 mg/kg24h divided in four doses.

a. what is the child's weight in kg?

b. what is the safe dose range for this child every 24 hours?

c. Is the order safe ?

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Solutions

Expert Solution

a. what is the child's weight in kg?

1 LB is equal to 0.453592 kg

40 lb is equal to 18.1437kg

The child weight is kg is: 18

b. what is the safe dose range for this child every 24 hours?

Dose Forms Discontinued in US [oral susp not benefit. as brand; see generic] contaminations, bacterial [25-50 mg/kg/day PO separated q6-12h]

Max: 4000 mg/24h; Info: measurement, length fluctuate by disease compose, seriousness; may give 50-100 mg/kg/day PO separated q6h for extreme contamination otitis media [75-100 mg/kg/day PO partitioned q6h]

Max: 4000 mg/24h pharyngitis, streptococcal [>1 yo]

Dosage: 40 mg/kg/day PO partitioned q12h x10 days; Max: 500 mg/measurement group procured pneumonia, bacterial

[>3 mo]

Dosage: 75-100 mg/kg/day PO partitioned q6-8h x7-10 days

UTI, uncomplicated

[>15 yo]

Dosage: 500 mg PO q12h x7-14 days skin/skin structure diseases, bacterial

[25-50 mg/kg/day PO partitioned q12h] *endocarditis prophylaxis, dental

[50 mg/kg PO x1]

Begin: 30-60min preceding system; Max: 2000 mg/dosage

renal dosing [adjust measurements frequency]

CrCl 30-50: give q8h; CrCl 10-29: give q12h; CrCl <10: give q24h; HD: give measurements after dialysis, no supplement; PD: no supplement

c. Is the order safe ?

The dose looks it is not safe. Because the maximum pediatric dose of keflex is 100 mg except UTI. This drug dose may consider safe only if the child suffering from UTI.

Nightingale answered 1 year ago

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