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In: Nursing

What are Drug-drug or drug-food interactions of Amlodipine?

What are Drug-drug or drug-food interactions of Amlodipine?

Solutions

Expert Solution

Amlodipine is a medication that is used to treat hypertension in an individual

Drug interactions of Amlodipine

Amlodipine usually is capable to potentially interact with some other drugs that is , including:

1)Simvastatin. It has interaction with Amlodipine so FDA has recommended to limiting the amount of simvastatin to about 20mg per day when talking along with Amlodipine

CYP3A4 inhibitors. These drugs specificaly are capable to inhibit the enzyme that is called as CYP3A4 and it can increase specificaly the concentration of the drug Amlodipine . The catagory of drugs'that come under this include diltiazem. Ritonavir , itraconazole and also , ketoconazole..

Cyclosporine also has been reported to show interaction with Amlodipine . Individual who underwent kidney transplantation and then , taking amlodipine as well as cyclosporine together will specificaly increase the levels of the cyclosporine in individual body.

Food drug interactions

Grapefruit Juice is having interaction with Amlodipine as it will the level of amlodipine in the blood stream of the individual

The use of alcohol as well as amlodipine togather can cause serve side effects in the individual .

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