Question

By what mechanism does neuromusuclar fatigue occur?

Answer 1

Mechanism of neuromuscular fatigue:the neuromuscular fatigue is a transient decrease in muscular performance usually seen as a failure to maintain or develop a certain expected force or power, the neuromuscular fatigue has central and peripheral origins and central fatigue preponderant during long duration low intensity exercises and involve a drop in the central command elicited by the activity of cerebral neurotransmitters and muscular afferent fibers and peripheral fatigue associated with an impairment of the mechanisms from excitation to muscle contraction may be induced by a perturbation of the calcium ion movements and an accumulation of phosphate and or decrease of the adenosine triphosphate stores and to compensate for the consequent drop in force production and the fatigue onset is associated with an alteration of the mechanisms involved in force production then the interaction between central and peripheral mechanisms leads to a series of events that ultimately contribute to the observed decrease in force production.