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In: Biology

explai the different types of mutations and how tgey occur

explai the different types of mutations and how tgey occur

Solutions

Expert Solution

Missense mutation, which results in a protein in which one amino acid is substituted for another. It is due to point mutation. Example sickle cell anemia

Nonsense mutation, in which a stop codon replaces an amino acid codon, leading to premature termination of translation. It is due to point mutation.

Frameshift mutation, which causes a change in the reading frame, leading to introduction of unrelated amino acids into the protein, generally followed by a stop codon.
It is due to insertion or deletion of DNA sequence. One form of beta-thalassemia.

Point mutation is due to ethylmethane sulfonate (EMS).

Chromosomal mutation
Inversion - One region of a chromosome is flipped and reinserted.
Duplication - A region of a chromosome is repeated.
Translocation - A region from one chromosome is aberrantly attached to another chromosome. Burkitt lymphoma.


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