What effect on phenotype will occur on the following types of mutations: 1. Base Substitution 2....

What effect on phenotype will occur on the following types of mutations:

1. Base Substitution

2. Thymine Dimers

3. Indels

4. Nucleotide Expansion

5. Larger lesions (duplication, deletions, inversion, translocation)

Expert Solution

1)-base pair changes have no effect on phenotype because changes occir in the non coding region of DNA sequence.

2)-Thymine dimer induced in human skin by sunlight and is a primary cause of skin cancer.

3)-indels mutation causes cancer.

4)-it causes pigmentary retinopathy.it affect cerebellum, spinal cord.

5)-short in stature, mental retardation.

gladiator answered 2 years ago

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