Question

Use at least two examples to explain why RNA secondary structure is important in the control of gene expression and replication in - RNA viruses.

Answer 1

RNA secondary structures, such as RNA hairpins. In plant tombusviruses utilize a number of long-range intra-genomic RNA–RNA interactions to regulate important events during infection of their hosts, i.e. viral translation and replication. viral RNA replication, also requires a long-range RNA–RNA interaction and necessary regulatory protien required for replication and translation of viral gene. Secondary structure of RNA, it can direct RNA folding, protect structural stability for messenger RNA (mRNA), provide recognition sites for RNA binding proteins, and serve as a substrate for enzymatic reactions indicate a role for this RNA–based interaction in the assembly of the viral replicase, which is responsible for executing viral RNA synthesis.  RNA secondary structure-predicting program mfold in an attempt to identify candidate RNA–RNA interactions. Ebola viral RNA also form RNA stem-loop structures at the 3? and 5? termini and panhandle structures between the termini of the genomic which ultimately control translation and replication.