a.) Lianne, a 35-year old female, suffers from hypercholesterolaemia and intractable, unstable angina. Her doctor, fearing...

a.) Lianne, a 35-year old female, suffers from hypercholesterolaemia and intractable, unstable angina. Her doctor, fearing it will lead to cardiovascular complications, prescribes her a calcium channel blocker and statin. Her doctor has selected pravastatin, but is still deciding between diltiazem or nifedipine. Explain i) the rationale of using a statin, ii) the way in which it is transported into cells, and iii) which calcium channel blocker would be most appropriate. (4½)

b). Lianne’s doctor decides on a suitable calcium channel blocker from the two options, and her treatment goes well. Explain i) how her calcium channel blocker will reduce angina, and ii) the way in which it will alter the heart rate.

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Expert Solution

Nightingale answered 1 year ago

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