Question

1. Design either a randomized controlled double blind experiment on a particular study of interest OR design a matched pairs study. State how you have been able to eliminate bias in your study.

Be highly specific in your answer. Your answer must be at least 8 COMPLETE sentences in length.

Answer 1

A Randomized Controlled Double Blind Experiment on a particular study of interest

Research question: Is the new drug more effective in curing a disease as compared to standard drug

Step 1: Randomly select sample of size n for the population of persons suffering from the disease

Step 2: Allocate randomly each participant to either of the 2 groups. Group 1: Control Group and Group 2: Experimental Group

Step 3: The allocation will be carried out by an independent statistician. Neither the exprimenter nor the participant will know which group each participant is allotted so that the experiment becomes double blind.

Step 4: Group 1: Control Group will be given standard drug which will look same as new drug

Step 5: Group 2 Experimental Group will be given new drug which will look same as standard drug

Step 6: At the end of the experiment, the data will be consolidated by the independent statistician as follows:

Number of persons recovered in Group 1: Control Group

Number of persons recovered in Group 2: Experimental Group

Step 7: Conduct 2 Independent Samples t test to find out whether the Group 2: Experimental Group has significantly more recoveries as compared to Group 1: Control Group

Step 8: Randomization of participants to either of the 2 groups makes the sample proper representative of population, controlling any confounding variables. Randomization ensures both groups in the study as similar as possible and reduce any bias or lurking variales that can influence the outcome of the tudy.