In: Nursing
1. List 4 possible causes of ABO discrepancies associated with the presence or absence of ABO antigens
2. List 4 possible causes of ABO discrepancies associated the presence or absence of ABO antibodies
1 Ans) When evaluating an ABO discrepancy it needs to be determined whether there is a problem with the FORWARD type (antigens on cells)
Problems With the Forward Type:
The forward type detects antigens present on the RED BLOOD CELLS.
False negative reactions in the forward type may occur due to:
False positive reactions may occur due to:
2 Ans) The REVERSE type (antibodies in serum/plasma) or BOTH:
Problems with the Reverse Type
The reverse type detects antibodies present in the SERUM or PLASMA.
False negative reactions in the reverse type may be due to weak or missing antibodies due to a variety of factors which influence the production of antibodies.
False positive reactions may be due to "unexpected antibodies", those antibodies other than anti-A or anti-B.