Question

1. Which is an advantage of antiemetic premedication prior to chemotherapy?
a) Decreased toxicity of anticancer drugs
b) Decreased pain during vomiting
c) Increased efficacy of anticancer drugs
d) Increased treatment compliance

2. Which of the following information is true about the ‘nadir’?
a) Chemotherapy should be withheld if it falls below 500/mm3
b) It occurs on the next day following a round of chemotherapy
c) It only occurs in cases of blood cancers
d) Therapy is effective if it falls below 800/mm³

3. What is the main difference between Vincristine & its analog Vinblastine?
a) Their efficacy
b) Their myelsuppressive power
c) Their administration routes
d) Their BBB X-ing capacity

4. When high-dose cyclophosphamide is employed, which of these approaches can mitigate some of the toxicity?
a) IV infusion administration
b) Administering before just before sleep
c) Hydration + Mesnex
d) PO Administration between meals

Answer 1

ANSWER.

1. d). Antiemetic premedication prior to chemotherapy increased

   treatment compliance.

2. a) Information true about Nadir is Chemotherapy should withheld

       if it falls below 500/mm3.

3. b) The main difference between Vincristine and Vinblastine are Their

         myelosupressive power.

        Vincristine is less myelosupressive than Vinblastine.

4.c) High dose of cyclophosphamide administration will cause cystitis due

       to convertion of cyclophosphamide to a active metabolite(acrolein) in the

       body.so it's toxic effect can reduced by giving Hydration and Mesnex.