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Explain ways in which systems biology can be used to predict the toxicity of drugs? How...

Explain ways in which systems biology can be used to predict the toxicity of drugs?

How can system biology approaches be used to identify how host-microbial interactions cause disease?

Please answer both questions

Solutions

Expert Solution

the above figure describes systems biology based methods(in sillico) of prediction of drrug toxicity.

2.

Systems biology studies the complex interactions between a large number of genes, proteins and other elements of biological networks and systems. Host-pathogen systems biology examines the interactions between the components of two distinct organisms, either a microbial or viral pathogen and its animal host or two different microbial species in a community. With the availability of complete genomic sequences of various hosts and pathogens, together with breakthroughs in proteomics, metabolomics and other experimental areas, the investigation of host-pathogen interaction on a multitude of levels of detail has come within reach. Using systems biology we can simulate host-pathogen interaction models since we already have large amounts of data regarding the genes, receptors and proteins involved in the process of infection.

gladiator answered 1 year ago
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