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In: Biology
Explain ways in which systems biology can be used to predict the toxicity of drugs? How...
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Expert Solution
the above figure describes systems biology based methods(in sillico) of prediction of drrug toxicity.
2.
Systems biology studies the complex interactions between a large number of genes, proteins and other elements of biological networks and systems. Host-pathogen systems biology examines the interactions between the components of two distinct organisms, either a microbial or viral pathogen and its animal host or two different microbial species in a community. With the availability of complete genomic sequences of various hosts and pathogens, together with breakthroughs in proteomics, metabolomics and other experimental areas, the investigation of host-pathogen interaction on a multitude of levels of detail has come within reach. Using systems biology we can simulate host-pathogen interaction models since we already have large amounts of data regarding the genes, receptors and proteins involved in the process of infection.
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