In: Biology
QUESTION 30
The normal activity of the retinoblastoma (Rb) protein in the cell is to:
A. block the initiation of anaphase during the cell cycle.
B. inhibit p53 activity.
C. induce cyclin–CDK complex formation.
D. regulate the progression of from G1 to S in the cell cycle.
E. suppress transcription of tumor-suppressor genes.
QUESTION 32
Which of the following is the major event associated with the retinoblastoma cancer?
A. |
a translocation resulting in the enhanced expression of an oncogene |
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B. |
inactivation of a major DNA repair system |
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C. |
a translocation involving chromosomes 9 and 22 |
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D. |
a mutation resulting in an activated RAS oncogene |
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E. |
both copies of a tumor-suppressor gene being inactivated |