Question

1. "If there is another outbreak of SARS or H5N1 influenza, which has killed more than 50% of those infected, would you consider using a DNA vaccine as protection?"

2. "Would you have your children or other family members treated with a DNA vaccine?"

Answer 1

1. Yes DNA vaccine would be considered for SARS and H1N1 outbreak.

The development of a vaccine to protect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an urgent biomedical need.

A DNA vaccine uses a gene from a virus or bacteria to stimulate the immune system. When the DNA vaccine is administered to a patient, the machinery in their cells makes a viral or bacterial protein which their immune system recognises as being foreign to the body.

2. Yes family members would treated with DNA vaccine.
DNA vaccines are an attractive approach for SARS vaccine development, as they offer many advantages over conventional vaccines, including stability, simplicity, and safety.

Finding a vaccine for this virus therefore remains a high priority. DNA vaccine encoding the spike (S) glycoprotein of the SARS-CoV induces T cell and neutralizing antibody responses, as well as protective immunity