You cross a mutant with phenotype 'a b c^+' to a mutant with the phenotype 'a^+b^+c'...

You cross a mutant with phenotype 'a b c^+' to a mutant with the phenotype 'a^+b^+c' and test cross the F1. Given this genetic map, predict the phenotypes observed in the offspring, and the number of each expected in a population of 2500 (show your work).

c < 19 m.u. > a <8 m.u. > b

Expert Solution

The steps involved in this problem:

1. Calculation of DCO from COC
2. Calculation of SCO and
3. Calculation of PCO.

1. Calculation of DCO freequency :
As the interference not mentioned here, providing the solution by taking the interference as 0. so,

COC = 1.
COC = Prop of ODCO/ Prop of EDCO.
=> 1 = Prof of ODCO/ (19/100 X 8/100) => DCO = 1 X 0.19 X 0.08 = 0.0152

The Freequency of DCO = 0.0152 *1000 = 38.

2. Calculation of SCO:.
The Distiance between two genes= Prop of SCO+ Prop of DCO.
So, Prop of SCO = Distiance between two genes - Prop of DCO.
The freequency = Prop of SCO * Total no of progeny

Between first pair of genes =
The Distance = 19, The proportion = 19/100 = 0.19
Prop of SCO = 0.19- 0.0152 = 0.1748
The freequency = 0.1748 * 2500 = 437.

Between second pair of genes =
The Distance = 8, The proportion = 8/100 = 0.08
Prop of SCO = 0.08- 0.0152 = 0.0648
The freequency = 0.0648 * 2500 = 162.

3. Calculation of PCO:

Parental combinations = Total freequency - SCO - DCO
=> 2500- 437 - 162- 38 = 1863

gladiator answered 2 years ago

(i) What is it about a mutant phenotype that classifies the mutation as “temperature-sensitive”?

a) (i) What is it about a mutant phenotype that classifies the mutation as “temperature-sensitive”? (ii) How is this type of phenotype explained by protein behaviour? b) Would the following types of mutations most likely have: severe effects, mild effects, or no effect on protein function? Briefly explain your answers. Note that there may be more than one correct answer, but you need only to give one sensible answer and explain your reasoning. (i) A nonsense mutation occurring in...

What would be the predicted phenotype of an E. coli mutant that contains a mutation in...

What would be the predicted phenotype of an E. coli mutant that contains a mutation in the cheA gene that abolishes its autophosphorylation activity? State the predicted phenotype. What kind of motility would it display?

A female fruit fly with the recessive mutant phenotype of white eyes and miniature wings is...

A female fruit fly with the recessive mutant phenotype of white eyes and miniature wings is mated with a male possessing the wild-type phenotype of red eyes and normal wings. Among the F1s, all the females are wild-type while all the males exhibit the mutant phenotype. The F2s resulting from a test cross exhibit predominantly (63%) parental phenotypes. How do you explain these results?

Will a pin1 mutant (loss-of-function) plant produce leaves? What would be the expected phenotype of a...

Will a pin1 mutant (loss-of-function) plant produce leaves? What would be the expected phenotype of a pin1 mutant plant? Briefly explain your answer

In plants, twisted leaves, a hypothetical mutant phenotype, may be caused by either a chloroplast gene...

In plants, twisted leaves, a hypothetical mutant phenotype, may be caused by either a chloroplast gene (CT = normal; Ct = twisted) or a recessive nuclear gene (NT = normal; Nt = twisted). Assume chloroplast DNA is maternally inherited. Predict the genotypic and phenotypic ratios in the offspring of the following crosses: a. CT NtNt female x Ct NTNT male b. Ct NtNt female x CT NTNT male c. F1 male from cross (a) x F1 female from cross (b)

1. Which of the following represents the phenotype of an organism? a. heterozygous b. dihybrid c....

1. Which of the following represents the phenotype of an organism? a. heterozygous b. dihybrid c. AaBb d. aa e. green pods 2. The heterogametic sex determines the sex of the progeny. True or false??

How to do cross product of |(B-A)x (C-A)|

compare and contrast the following items: a. dominant and recessive b. genotype and phenotype c. homozygous...

compare and contrast the following items: a. dominant and recessive b. genotype and phenotype c. homozygous and heterozygous d. monohybrid cross and test cross e. dihybrid cross and trihybrid cross there is no more. just have to compare a) to eachother, b) to eachother and so forth

Consider the cross: A/a; b/b; C/c; D/d; E/e x A/a; B/b; c/c; D/d; e/e a) what...

Consider the cross: A/a; b/b; C/c; D/d; E/e x A/a; B/b; c/c; D/d; e/e a) what proportion of the progeny will phenotypically resemble the first parent? b) what proportion of the progeny will genotypically resemble neither parent?

1. Define test cross Answer 2. You mate two organisms one with a dominant phenotype and...

1. Define test cross Answer 2. You mate two organisms one with a dominant phenotype and one with a recessive phenotype. For which organism are you sure of the genotype and for which are you unsure of the genotype. Explain your answers. Answer 3. A geneticist crosses a green pea plant with a yellow pea plant and all the offspring are yellow. He accidentally mixes the seeds. a. What is the dominant phenotype and which is the recessive phenotype Answer...

Question