In: Nursing
For each of questions 1–4, select and support the most appropriate response, andexplain why each of the other statements is eliminated.
1. Mitochondrial
a. inheritance is maternal. - INCORRECT
b. DNA is linear.
c. function depends on nuclear genes.
d. diseases have minor effects.
e. two of the above CORRECT (5 marks)
2. Genomic imprinting is an example of
a. pleiotropy.
b. heterogeneity.
c. epistasis.
d. differential gene expression. - CORRECT
e. a phenocopy. (5 marks)
3. A typical human female child
a. has ooctyes in the process of meiosis.
b. has indifferent gonads.
c. degraded the Müllerian ducts.
d. inactivated the SRY gene.
e. requires information from only one of her X chromosomes.- CORRECT (5 marks)
4. Heritability describes the
a. genetic composition for a trait in a particular population.
b. phenotypic variation of a trait in a particular population.
c. variation in a phenotype caused by the environment.
d. proportion of genetic contribution to a trait in a particular population.- CORRECT
none of the above.
!!!!CAN YOU PLEASE EXPLAIN WHY THE OTHER ANSWERS ARE INCORRECT!!!!1
1. Correct answer:- (e) two of the above
Explanation:-
(a) In human, sperm-derived paternal mitochondria enter the oocyte
cytoplasm.
-After fertilization, mitochondrial DNA is never transmitted to the
offspring. Hence interitance is not maternal.
(b) Mitochondrial DNA is a double helixed circular molecule.
(c) mitochondrial Functions ( oxidative phosphorylation) depend
upon factors which are encoded both by the mitoochondrial DNA and
nuclear genome.
(d) Mitochondrial chromosome is not inheritable so its diseases are
not inherited,and have minor effect.
2. Correct answer:- (d) differential gene
expression
Explanation:-
(a) pleiotropy:-it is defined as a phenomenon in which one (usually
mutant) allele influences two or more apparently unrelated
phenotypic traits.
- shows how mutation in one gene leads to disease.
(b) heterogeneity:- state of being heterozygous, containing
different allele in a single gene.
(c) Epistasis:- when two different genes which are not alleles,
both affect the same character in such a way that the expression of
one inhibit or suppresses the expression of the other gene, called
epistasis.
(d) differential gene expression:- it shows that all cells in the
body have the same genome, but express different parts on it
(differential expression) depending on cell type and tissue.
- genomic imprinting based on it.
3. Correct answer:- (e) requires information from only one of
her X chromosomes.
Explanation:-
(a) in oocyte only found during mitosis.
(b) female has development of gonads differently.
(C) fusion of mullerian