Question

In which of the following does the main pathophysiological mechanism not depend on hydrostatic pressure increase?

a. Edema seen in Kwashiorkor's disease

b. lower extremity edema due to congestive heart failure

c. Edema due to constrictive pericarditis

d. ascites in liver cirrhosis

e. Edema in the lower extremity in nephrotic syndrome

Answer 1

answer is e

because edema in nephrotic syndrome is due to changes in oncotic pressure [DECREMENT IN PLASMA ALBUMIN] not hydrostatic pressure

IN OTHER OPTIONS EDEMA IS DUE TO CHANGES IN HYDROSTATIC PRESSURE

c] IN CONSTRICTIVE PERICARDITIS - the restricted distensibility of the atria in constructive pericarditis ,limits the secretion of atrial natriuretic factor and thus,reduces its natriuretic and diuretic effects .this result in retension of water and sodium leads to edema

a] edema in kwarshiorkor is characterised by peripheral edema due to loss of fluid balance between hydrostatic and oncotic pressure

b]in congestive heart failure edema is due to increased capillary hydrostatic pressure [as occurs when venous pressures become elevated by gravitational forces ]

d]ascitis in liver disease is due to changes in hydrostatic fluid pressure in the liver interstitium [portal and subcapsular spaces]

e]edema in nephrotic syndrome is due to