Question

The nurse provides information to a student nurse about antibiotic therapy for a patient with cystic fibrosis (CF) who experiences a productive cough, PaO ₂ of 50 mmHg, arteriolar vasoconstriction, and cor pulmonale. Which statement made by the student nurse indicates effective learning?

a. "The patient will need one dose of an intravenous antibiotic."

b. "The patient will require prolonged high-dose antibiotic therapy."

c. "For mild disease exacerbations, intravenous antibiotic therapy will be required."

d. "For mild disease exacerbations, intravenous antibiotics are preferred over oral antibiotics."

Answer 1

In the above case the patient is having pulmonary exacerbation as you can see that the alveolar partial pressure of oxygen is 50mm of hg..

in such case the patient has to given a prolonged parentaral dose of antibiotic therapy for atleast 15 days.

as we know that,

for chronic management of cystic fibrosis,

exogenous pancreatic enzymes taken with meals, nutritional supplementation, anti-inflammatory medication, bronchodilators, and chronic or periodic administration of oral or aerosolized antibiotics (e.g., as maintenance therapy for patients with P. aeruginosa). Recombinant DNAse aerosols (degraded DNA strands that contribute to mucus viscosity) and nebulized hypertonic saline (serves to augment PCL depth, activate mucociliary clearance, and mobilize inspissated airway secretions) are administered routinely.

But pulmonary exerbations  is commonly managed by hospital admission for frequent chest physiotherapy and parenteral antibiotics directed against serious (and often multiply resistant) bacterial pathogens.

Typical inpatient antibiotic coverage includes combination drug therapy with an aminoglycoside and β-lactam for at least 14 days. Maximal improvement in lung function is often achieved by 8–10 days in this setting

conclusion: option b is the correct answer