Which of the following is not an executioner of apoptosis?

cytochrome C

BH3-only protein Bid

BH3-only proteins Puma and Noxa

Bc12

Fas ligand

none of the above are executioners of apoptosis

Expert Solution

ANSWER Bcl2

Apoptosis is the process of programmed cell death

in the above question it states that in the following which was not helping the apoptosis process so it can also called as anti apoptosis process

from the following options Bcl2 was not causing the apoptosis so it can also known as anti apoptosis

cell death can be initiated through one of two pathways.

In intrinsic pathway the cell kills itself because it senses cell stress,
In extrinsic pathway the cell kills itself because of signals from other cells.
Both pathways causes cell death by activating caspases,
which are proteases, or enzymes that degrade proteins.

mechanism

so many mechanisms are i exixts in termination of cell death

Bcl2 having the following action by activation or inactivation of an inner mitochondrial permeability transition pore, which is involved in the regulation of matrix Ca²⁺, pH, and voltage
in some conditions it will induce or inhibit the release the cytocrome C into the cytosol. where cytocrome C activates caspase-9 and caspase-3, leading to cell death

gladiator answered 2 years ago

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