Question

what is 5 different methods that can increase the affinity of a certain drug to its receptor

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Answer 1

Affinity is a measure of the tightness that drugs bind to the receptor. receptors are macromolecules in chemical signaling between each cell. it regulates cellular biochemical processes like protein phosphorylation, ion conductance, and enzymatic activity directly and indirectly.  Agonist that bind different sites on the receptors. agonist activates receptors for active response. antagonists prevent receptor activation by increasing cellular function and decreasing cellular function by blocking the action of substance or drugs. conventional agonist increases the proportion of receptors activation. Reversible antagonist stabilizes the chemical bond with their receipts. The action of ligands at receptors depends upon the binding and effects on the receptors.G protein couples receptors that is a major protein located in the cell membrane and it is activated by ligand to convert extracellular signals into intracellular. agonist bind to G protein coupled resptors and increase the affinity of the drugs.