What would you expect from a person's EMG who has Muscular Dystrophy who is asked to...

What would you expect from a person's EMG who has Muscular Dystrophy who is asked to lift a weight? How would that differ from a person with Myasthenia gravis?

During repeated skeletal muscle contraction, what happens to calcium within a single motor unit that may lead to fatigue? What is its overall effect?

Why is high intensity anaerobic exercise limited in duration?

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Expert Solution

The initial changes in the EMG of a person suffering from Muscular dystrophy is increased percentage of the polyphasic potentials although other MUAPs( Motor unit action potential duration) parameters could be normal. A decreased amplitude, area and MUAPs duration, along with the decrease of IP amplitude and amplitude size.

The EMG of a patient suffering from Mysthenia Gravis is usually normal. However repetitive stimulation of a nerve may demonstrate decreased action potential.

Depolarization of skeletal muscle cell results in a muscle action potential. This leads to release of calcium from sarcoplasmic reticulum into the local junctional space. this is called as calcium spark. the troponin C takes up this calcium and leads to production of force or movement.

The sarcoplasmic reticulum calcium-ATPase (SERCA) actively pumps calcium back into the sarcoplasmic reticulum. And the calcium level declines back to normal levels

Sydney Mullin answered 1 year ago

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