What would you expect from a person's EMG who has Muscular Dystrophy who is asked to...

What would you expect from a person's EMG who has Muscular Dystrophy who is asked to lift a weight? How would that differ from a person with Myasthenia gravis?

During repeated skeletal muscle contraction, what happens to calcium within a single motor unit that may lead to fatigue? What is its overall effect?

Why is high intensity anaerobic exercise limited in duration?

Expert Solution

The initial changes in the EMG of a person suffering from Muscular dystrophy is increased percentage of the polyphasic potentials although other MUAPs( Motor unit action potential duration) parameters could be normal. A decreased amplitude, area and MUAPs duration, along with the decrease of IP amplitude and amplitude size.

The EMG of a patient suffering from Mysthenia Gravis is usually normal. However repetitive stimulation of a nerve may demonstrate decreased action potential.

Depolarization of skeletal muscle cell results in a muscle action potential. This leads to release of calcium from sarcoplasmic reticulum into the local junctional space. this is called as calcium spark. the troponin C takes up this calcium and leads to production of force or movement.

The sarcoplasmic reticulum calcium-ATPase (SERCA) actively pumps calcium back into the sarcoplasmic reticulum. And the calcium level declines back to normal levels

Sydney Mullin answered 2 years ago

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