Describe and contrast stages i,ii,and iii of lactogenesis.

Expert Solution

ANSWER- Lactogenesis as the word comprises of lactose and genesis. It means ability to secret the milk. It includes all the changes that in the mammary epithelium to fully mature alveolar cells after the parturition. It means childbirth. The whole lactation process is under the control of endocrine system. Hormones that are involved in secretion of milk Prolactin and Oxytocin.

Mainly there are three stages of lactogenesis

1. Lactogenesis I- ( birth to 2-5 days) milk formation begins.

Mammary gland become competent to secret milk.

Lactose, Total proteins, and immunoglobulin circulation increase within glandular fluid where as sodium and chloride gradually decreased.

Levels of progesterone and estrogen are high and help to hold the milk.

2. Lactogenesis II- It begins 2-5 days after birth

Triggered point - Drop in the level of progesterone after delivery.

Eventually elevated the levels of prolactin and cortisol to mobilise the nutrients.

Switch from endocrine to autocrine.

3. Lactogenesis III- It begins after 10 days of birth. When milk composition becomes stable.

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Describe and contrast stages i,ii,and iii of lactogenesis.

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