In: Biology
6a. Loss of p53 function occurs in the majority of human tumors. Name two ways in which loss of p53 function contributes to a malignant phenotype.
b. explain the mechanism by which the following agents cause loss of p53 function: a) human papillomavirus and b) benzy(a)pyrene.
Ans:a:The two ways in which loss of p53 function contributes to a malignant phenotype are ;Mutation in p53 gene and damage to p53 gene where tumor suppression is severely compromised.
Ansb:
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