In: Biology
The process of copying / replicating chromosome DNA accurately for its transmission from generation to generation is known as Replication. A new complimentary strand is synthesized opposite to parental template strands producing two identical DNA helixes.
There are 3 basic steps of this process-
1)Initiation 2) elongation 3) termination
1)Initiation - DNA replication begins at Ori sequence, helicase enzyme opens up the parental helix and primer is laid by the enzyme Primase.
2) Elongation - DNA polymerase elongates the primers by nucleophillic attack of 3'OH group on inner phosphorous atom of incoming dNTPsand forms leading and lagging strands against templates.
3) termination - the proceee of replication ends after copying the entire chromosome of the organism. In prokaryotes ter-tus complex inhibits the replication fork and stops it while in eukaryotes Telomerase catalyse the replication at ends / Telomeres and stops the process.