In: Biology
15. Induced pluripotent stem cells are an attractive
approach to cell replacement therapy because____.
a. They can be induced to develop into many different types of
tissues
b. They can be derived from differentiated cells
c. acquisition of these cells does not require killing of an
embryo
d. They can be studied using techniques that are already developed
from work with embryonic stem cells
e. All are correct. i.e. these are reasons why induced pluripotent
stem cells are an attractive alternative
14. Cancer Is a genetic in that it can be traced to
alterations within specific genes. But, in most cases it is not an
inherited disease. This is because the genetic alterations in most
cancers ____ during the lifetime of the affected individual.
A. Arise mostly in the DNA of somatic cells
B. Are usually introduced by bacteria
C. Arise mostly in sperm and egg cells
D. Are usually introduced by viruses
7. Oncogenes arise from proto-oncogenes, which of the
following statements BEST explain the presence of pro-oncogenes in
the human genome?
a. Proto-oncogenes are mutant versions of normal genes
b. Proto-oncogenes are introduced by viral infections
c. Proto-oncogenes are two non-functional genes that are combined
to gain a new function through translocation.
d. Proto-oncogenes are normal genes that promote cell division
Ans15. e. All are correct. i.e. these are reasons why induced pluripotent stem cells are an attractive alternative.
Explanation- Induced pluripotent cells are the stem cells that are developed from already differentiated cells by expression of genes that are present in embryonic cells. These are able to differentiate into different cells as embryonic cells and do not require killing of embryos and studied as embryonic cells only.
Ans14. A. Arise mostly in the DNA of somatic cells.
Explanation- Somatic cells are not passed from parents to offsprings. Hence, cancer developed by mutation in these cells will not be inherited.
Ans7. d. Proto-oncogenes are normal genes that promote cell division.
Explanation- Proto-oncogenes are the normal genes present in normal cells which perform different functions in cells one of them is cell division. These genes once activated lead to cancers by unregulated cell growth.