Question

In the roux-en-Y gastric bypass surgery, food travels directly from the esophagus into the jejunum, and the duodenum is excluded from the flow of nutrients. Which of the following is an expected consequence of this change in the anatomy of the digestive tract?

Group of answer choices

increased secretion of amylase after a meal

an increase in the amount of secretin that can be found in the blood after a meal

an increase in the amount of gastrin that can be found in the blood after a meal

a decrease in the amount of CCK that can be found in the blood after a meal

decreased absorption of electrolytes in the small intestine

Answer 1

Roux en Y gastric bypass surgery involves creation of a smaller stomach and directly connect it to small intestine by passing some part of Jejunum and Duodenum. Two limbs are created in this procedure. One limb is Roux limb and other one is Biliopancreatic limb, which transport secretion from the pancreas and liver.

The main consequences of this change are

A decrease in the amount of CCK in blood:

Cholecystokinin hormone is released by linings of duodenum and through small intestine it binds to Pancreatic cells to produce large amount of digestive enzymes.

So in case of bypassing the duodenum the amount of Cholecystokinin decrease in blood.

Decrease absorption of electrolytes in small intestines:

Malabsorption of micronutrients and electrolytes can be cause due to shortage length of common channel of small intestine. Firstly decrease in volume of the stomach, absence of duodenum and first portion of Jejunum are bypassed resulting in malabsorption.

Micronutrients and electrolytes gets small surface area to be completely absorbed. So these micronutrients compete for absorption.