Question

what will happen if the cell doesnt have any FAD left in citric cycle, cellular resporation, ocidative phosphorylation, ETC.

explain in detail.

Answer 1

Cellular respiration is the process of breakdown of glucose into carbon dioxide and water for the generation of ATP molecules. ATP are high energy rich molecules which are used by the cell to perform its metabolic activities.

FAD is an electron carrier which is used in citric acid cycle. It enters electron transport chain taking place in inner mitochondrial membrane. It carries electrons from acetyl coenzyme A to II Complex of electron transport chain. In this way it participates in electron transport chain.

If this molecule is not present in the cell, then there will be no electrons donated by this molecule to the second Complex of electron transport chain. This will lead to the reduction in the number of electrons being transported from one electron carrier to the other during electron transport chain. If the number of electrons are reduced, then the number of protons which will be pumped from mitochondrial Matrix to intermembrane space will also be reduced. If the number of protons are reduced, then the differential concentration of protons generated across inner mitochondrial membrane will not have enough electrochemical energy for the synthesis of ATP. Therefore the amount of ATP is synthesized in the end of electron transport chain by oxidative phosphorylation will reduce.

Therefore, the overall effect will be a deficiency in the number of ATP molecules synthesized after oxidative phosphorylation.

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